Dr. Rodeo is a clinician-scientist at the Hospital for Special Surgery, with appointments in the Department of Orthopaedic Surgery (Sports Medicine and Shoulder Service) and the Research Department (Laboratory for Soft Tissue Research). He is Professor of Orthopaedic Surgery, Weill Cornell Medical College and Co-Chief of the Sports Medicine and Shoulder Service at The Hospital for Special Surgery. His specializes in sports medicine injuries of the knee, shoulder, ankle, and elbow. He also performs arthritis surgery of the knee and shoulder, including joint replacement surgery. He has specific expertise in complex knee reconstruction (including meniscus transplantation, cartilage resurfacing, osteotomy, and ligament reconstruction), treatment of shoulder instability, and rotator cuff tendon repair.  His research focuses on the basic biology of tendon and ligament healing, meniscal allograft transplantation, and rotator cuff repair. Dr. Rodeo is a former competitive swimmer and provides care for local swimming programs.

He is associate team physician of the New York Giants Football Team, and he also served as Team Physician for the 2004 and 2008 U.S.A. Olympic Team.